On the offensive side of the ball, the personnel of each will make their Week 5 game in Pittsburgh seem very much like practice.
The Steelers have invested middle round picks at the wide receiver position, striking a bonanza with Mike Wallace (3rd, 2009), Antonio Brown (6th, 2010) and Emmanuel Sanders (3rd, 2010). The Eagles took DeSean Jackson in the 2nd round of the 2008 NFL Draft, and Jeremy Maclin in the 1st round of the 2009 draft. Throw in Jason Avant, a 4th round pick in 2006, you have the Eagles top three wide receivers.
Each team though, gets a lot of use out of their tight ends. Heath Miller leads the Steelers with four touchdown receptions in three games, and Brent Celek is second on the Eagles with 18 catches and a 17.5 yard average.
The Steelers have had more success scoring (25.7 points per game vs. 16.5 for Philadelphia), and the Eagles have a considerably better running game (145.8 yards per game vs. the Steelers' 65 yards per game).
A big part of Philadelphia's success on the ground is due to running back LeSean McCoy - a University of Pittsburgh product taken in the second round of the 2009 draft. The Steelers will have Rashard Mendenhall back for Week 5. He was taken in the first round of the 2008 draft.
Both coaches have had outstanding careers to this point. Mike Tomlin has a .675 winning percentage since taking over in 2007 (56-27) while Philadelphia's Andy Reed has a .610 (128-82-1) win percentage.