Colon was a fourth round pick out of Hofstra in 2006, eventually earning the team's starting right tackle position by 2007. He was the Steelers' starting right tackle when they defeated the Arizona Cardinals in Super Bowl XLIII, and signed a $2.2 million deal in restricted free agency in 2009.
Injuries decimated his career in Pittsburgh. He tore his Achilles tendon in 2010, forcing him out of the entire 2010 season - one in which the Steelers advanced to the Super Bowl. In Week 1 of 2011, he tore a triceps muscle, costing him the entire next season as well. Between those two injuries, Colon signed a five-year, $29 million contract.
The Steelers released Colon after the 2012 season, and he signed a one-year deal with the Jets. They signed him to a second one-year contract this offseason.