Update: Post Gazette reporter Ed Bouchette tweeted during halftime a team official said Pouncey's situation was "not good," strongly indicating his injury was as bad as it looked.
Kelvin Beachum remained at center, as the Steelers offensive line has been dominated in this game.
Pouncey "not good" according to one #Steelers official. Possible ACL. Getting MRI— Ed Bouchette (@EdBouchette) September 8, 2013
Update: Steelers center Maurkice Pouncey is heading to a hospital for an MRI on his right knee.
Pouncey headed to hospital for MRI and is done for the game. Big break for #Titans— John Glennon (@glennonsports) September 8, 2013
It doesn't look good, to put it mildly.
The Steelers needed just one drive to suffer their first injury on their offensive line. This one appears to be a significant one to three-time All Pro center Maurkice Pouncey.
Steelers Maurkice Pouncey carted off. Big blow— Chris Mortensen (@mortreport) September 8, 2013
He was rolled on while blocking during the Steelers' first offensive possession in Week 1 against the Tennessee Titans.
The drive came just after the Steelers got two points on a safety by kick returner Darius Reynaud on the opening kickoff. The Steelers were 3-for-3 on third downs on the drive, and looked very strong offensively. However, running back Isaac Redman fumbled at the goal line, giving the Titans a touchback - a continuation of one of the most active five minutes the Steelers have seen in quite a while.
Not to speculate, but it simply did not look good for Pouncey. Kelvin Beachum, who started at tight end in the game, replaced him at center.
We'll have more updates as they happen.