The Steelers had the football to start the second quarter, and despite a holding call and a sack, Roethlisberger attacked the Minnesota secondary again. The victim this time was Trae Waynes as he was called for a defensive pass interference penalty against Martavis Bryant.
Two plays later the Steelers cashed in on a shovel pass from Roethlisberger to JuJu Smith-Schuster, who scored on his first NFL reception, to make the score 14-0, after the Bowell point-after.
Case Keenum slowly got himself acclimated to starting the game, and was able to put together a drive which put Minneosta in Pittsburgh territory for the first time. However, the drive stalled, and the Vikings settled for a Kai Forbath field goal to cut into the Pittsburgh lead 14-3.
After a series of punts, the score would remain 14-3 heading into the half, with the Vikings set to receive the ball in the second half.