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NFL Odds and Predictions: Picking the full Week 10 slate of games against the spread

We make our picks against the spread and versus the totals for every game on the NFL schedule in Week 10.

NFL: Indianapolis Colts at Pittsburgh Steelers Charles LeClaire-USA TODAY Sports

The Pittsburgh Steelers might have already won the most important game of the week, but there are still one or two games left worth watching on Sunday. After a week in which Jeff Hartman went 10-2 against the spread and 9-3 versus the totals, he will hopefully guide you down the right path with his selections for Week 10 once again, while I offer no such promises having gone 6-6 ATS and 7-5 versus the totals.

While Week 9 featured a number of close spreads, it is a rather different story this Sunday. Only three games are separated by a field goal or less and five games are currently showing a spread of more than a touchdown. As 16.5-point favorites over Arizona Cardinals, the Kansas City Chiefs will be the biggest favorite of any game this year if the line has maintained this level come kickoff.

With the Cincinnati Bengals (+5.5) facing a tough test at home against the New Orleans Saints (-5.5), the Steelers might yet end the week with an even bigger lead in the race for the division title. The Baltimore Ravens are on a bye in Week 10 and the Cleveland Browns are already so irrelevant it does not matter what happens with them for the rest of the season.

Selections have been made using the consensus Las Vegas odds from as per Friday night and we encourage you to play along with us by adding your picks below.