Previewing the Pittsburgh Steelers vs. Buffalo Bills Week 5 showdown

The Pittsburgh Steelers and Buffalo Bills are two teams who know each other well considering they are AFC rivals and have seemingly played each other every season the past few years. For these teams, the game in Week 5 is as big one. Throw in the fact the Steelers are on a three-game losing streak, and this game gets even more attention.

Here is the game preview for the Steelers and Bills for their Week 5 matchup in Buffalo.

Teams (Records)

Pittsburgh Steelers: 1-3
Buffalo Bills: 3-1

Odds (Courtesy of DraftKings Sportsbook)

Bills (+14.0)
OVER/UNDER: 46.0
Moneyline: Steelers +650; Bills -950

Odds/lines subject to change. T&Cs apply. See draftkings.com/sportsbook for details.

Last 5 Games in series

Steelers: 3-2

Matchup History

Pittsburgh Steelers lead series 17-11-0

Injury Report

(Note: This will be updated throughout the week as more injury reports are released)

Steelers

Game Status

• CB Cameron Sutton - Questionable
• CB Ahkello Witherspoon - Out
• S Terrell Edmunds - Questionable

Friday, October 7

WR Diontae Johnson (Hip) - FP
CB Cameron Sutton (Groin/Hamstring) - LP
CB Ahkello Witherspoon (Hamstring) - DNP
CB Levi Wallace (Foot) - FP
S Terrell Edmunds (Concussion) - LP
S Minkah Fitzpatrick (Knee) - FP
OL Mason Cole (Foot) - LP
DL Chris Wormley (Ankle) - FP
DT Cameron Heyward (Ankle/Elbow) - FP

Thursday, October 6

WR Diontae Johnson (Hip) - LP
CB Cameron Sutton (Groin/Hamstring) - LP
CB Ahkello Witherspoon (Hamstring) - DNP
CB Levi Wallace (Foot) - LP
S Terrell Edmunds (Concussion) - LP
S Minkah Fitzpatrick (Knee) - LP
OL Mason Cole (Foot) - LP
DL Chris Wormley (Ankle) - LP
DT Cameron Heyward (Ankle/Elbow) - LP

Wednesday, October 5

CB Cameron Sutton (Groin/Hamstring) - LP
CB Ahkello Witherspoon (Hamstring) - DNP
CB Levi Wallace (Foot) - LP
S Terrell Edmunds (Concussion) - DNP
S Minkah Fitzpatrick (Knee) - DNP
DL Chris Wormley (Ankle) - LP
DT Cameron Heyward (Ankle/Elbow) - LP

Bills

Game Status

• CB Christian Benford (Hand) - Out
• WR Jamison Crowder (Ankle) - Out
• LB Tremaine Edmunds (Hamstring) - Questionable
• TE Dawson Knox (Foot/Hamstring) - Out
• WR Jake Kumerow (Ankle) - Out
• WR Isaiah McKenzie (Concussion) - Questionable
• DT Ed Oliver (Ankle) - Questionable
• DT Jordan Phillips (Hamstring) - Questionable
• S Jordan Poyer (Ribs) - Out

Friday, October 7

CB Christian Benford (Hand) - DNP
WR Jamison Crowder (Ankle) - DNP
WR Gabe Davis (Ankle) - FP
WR Stefon Diggs (Vet Rest) - DNP
LB Tremaine Edmunds (Hamstring) - DNP
DT DaQuan Jones (Vet Rest) ---
TE Dawson Knox (Foot/Hamstring) - DNP
WR Jake Kumerow (Ankle) - DNP
CB Cam Lewis (Forearm/Knee) - FP
WR Isaiah McKenzie (Concussion) - LP
LB Von Miller (Vest Rest) - DNP
C Mitch Morse (Elbow) - FP
OL Justin Murray (Foot) - FP
DT Ed Oliver (Ankle) - LP
DT Jordan Phillips (Hamstring) - LP
S Jordan Poyer (Ribs) - DNP
G Rodger Saffold (Vet Rest) ---

Thursday, October 6

CB Christian Benford (Hand) - DNP
WR Jamison Crowder (Ankle) - DNP
WR Gabe Davis (Ankle) - FP
LB Tremaine Edmunds (Hamstring) - DNP
DT DaQuan Jones (Vet Rest) ---
TE Dawson Knox (Foot/Hamstring) - DNP
WR Jake Kumerow (Ankle) - DNP
CB Cam Lewis (Forearm/Knee) - FP
WR Isaiah McKenzie (Concussion) - LP
LB Von Miller (Vest Rest) ---
C Mitch Morse (Elbow) - FP
OL Justin Murray (Foot) - LP
DT Ed Oliver (Ankle) - LP
DT Jordan Phillips (Hamstring) - LP
S Jordan Poyer (Ribs) - DNP
G Rodger Saffold (Vet Rest) ---

Wednesday, October 5

CB Christian Benford (Hand) - DNP
WR Jamison Crowder (Ankle) - DNP
WR Gabe Davis (Ankle) - Full
LB Tremaine Edmunds (Hamstring) - DNP
DT DaQuan Jones (Vet Rest) - DNP
TE Dawson Knox (Foot/Hamstring) - DNP
WR Jake Kumerow (Ankle) - DNP
CB Cam Lewis (Forearm/Knee) - Full
WR Isaiah McKenzie (Concussion) - DNP
LB Von Miller (Vest Rest) - DNP
C Mitch Morse (Elbow) - LP
OL Justin Murray (Foot) - LP
DT Ed Oliver (Ankle) - LP
DT Jordan Phillips (Hamstring) - LP
S Jordan Poyer (Ribs) - DNP
G Rodger Saffold (Vet Rest) - DNP

News and Notes

As it pertains to the Buffalo Bills and Pittsburgh Steelers, these two teams couldn’t be on a more different trajectory heading into Week 5. The Bills (3-1) are considered the cream of the AFC crop. With Josh Allen at the helm, and Stefon Diggs running wild through defensive secondaries, Buffalo’s offense strikes fear into the opposition.

For the Steelers, their offense takes a new shape with Kenny Pickett taking over for Mitch Trubisky. With the rookie at the helm, it marks a new era of Steelers football, but that era is also a complete unknown. No longer is Ben Roethlisberger the steady rock of the Steelers organization. Will Pickett take over and be that guy for the Steelers for the next decade? It’s way too early to tell right now, but the answer to that question will begin in Buffalo on Sunday.

Defensively, the Steelers come into this Week 5 matchup with some serious question marks on the defensive side of the ball. With T.J. Watt still on Injured Reserve (IR), the team is also dealing with several key injuries throughout their secondary. Injured players include: Terrell Edmunds (concussion), Minkah Fitzpatrick (knee), Cam Sutton (groin/hamstring) and Ahkello Witherspoon (hamstring). If those names weren’t enough, the Steelers defensive captain, Cam Heyward, is also dealing with injuries to both his ankle and elbow.

It won’t be easy, and the oddsmakers know this. The Steelers are 14-point underdogs for the first time since the NFL/AFL merger. Can the Steelers keep it competitive? Could the do the unthinkable, like they did in Week 1 of 2021, and pull off an upset win?

The uphill climb for Pickett and the Steelers begins Sunday at 1 p.m. ET in western New York.

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Be sure to stay tuned to BTSC for the latest news and notes surrounding the black and gold for all the coverage of their game with the Bills in Buffalo in Week 5 of the 2022 regular season.