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Note: All rankings are for standard scoring leagues
1. Steelers WR Antonio Brown vs. Washington
Brown is likely your best bet in each week moving forward.
San Francisco's 28th-ranked run defense from a year ago didn't get any better this offseason.
3. Steelers RB DeAngelo Williams vs. Washington
Williams was the 4th-best back in fantasy last season despite getting 10 or more touches in just 10 games.
4. Falcons WR Julio Jones vs. Buccaneers
Tampa Bay was 14th in yards allowed last season, though they surrendered the 5th-most passing touchdowns in the NFL. Jones is a safe bet for 220 targets this season.
Beckham averages six catches for 65 yards and a touchdown in four career games against Dallas. High floor, higher ceiling.
6. Texas RB Lamar Miller vs. Bears
Miller should get 25 touches against one of the league's softest defensive units.
I have him lower than most since the Titans will likely play eight men in the box. Peterson is still a top-seven play because eight-man fronts have never stopped him before.
Robinson will look to build on a Pro Bowl season in a game that should feature plenty of points.
9. Packers WR Jordy Nelson vs. Jaguars
See above. Nelson should have a big day in his first game action since last August.
10. Texans WR DeAndre Hopkins vs. Bears
I could see Miller and the Texans' ground game eating into Hopkins' workload.
11. Cowboys RB Ezekiel Elliott vs. Giants
Elliott's upside is hampered by the capable veterans playing behind him. Dallas' offensive line, however, gives him a chance to lead the league in scoring every week.
With a rookie quarterback under center and playing against a sieve-like front-seven, new Eagles head coach Doug Pederson is going to run the ball.
13. Cowboys WR Dez Bryant vs. Giants
Bryant will go as rookie QB Dak Prescott goes, but the Giants' secondary was by far the worst in the NFL last season.
The Patriots have a top-tier defense, but the Cardinals' lethal trio of receivers should give Johnson some breathing room.
With Karlos Williams no longer on Buffalo's roster, McCoy should receive his biggest workload since his tenure in Philadelphia.
The Saints allowed 45 passing touchdowns last season, which led the league. The second place team in this category allowed just 36 scores.
17. Saints RB Mark Ingram vs. Raiders
Ingram was a top-12 running back last season despite missing four games.
This is very likely the lowest that I will rank Green all season. The Jets should be able to double- or triple-team the Bengals' lone vertical playmaker.
19. Falcons RB DeVonta Freeman vs. Buccaneers
Play him while you can, because backup RB Tevin Coleman is gunning for the starting job.
20. Jets WR Brandon Marshall vs. Bengals
Marshall was the third-best receiver in fantasy last season.
21. Saints WR Brandin Cooks vs. Raiders
Cooks was the definition of a boom-or-bust fantasy player last season, as the third-year receiver had seven games with 16 or more fantasy points, but scored eight or fewer points in his other nine contests.
22. Buccaneers WR Mike Evans vs. Falcons
Evans' touchdowns dropped from almost a dozen to just two last season. Look for him to approach his rookie totals.
23. Buccaneers RB Doug Martin vs. Falcons
Martin had the quietest 1,400-yard season in NFL history last year. Having been rewarded with a hefty contract extension, it is fair to wonder if he can do it again.
Hilton should be the primary benefactor of Andrew Luck's Comeback Player of the Year bid.
25. Bears WR Alshon Jeffery vs. Texans
The Bears will have to throw early and often. Jeffery will be a garbage time king this season.
26. Raiders RB Latavius Murray vs. Saints
I'm only high on Murray this week because the Raiders vs. Saints matchup promises to be a shootout.
Allen should see over a dozen targets in this game, but Marcus Peters and Kansas City's exceptional secondary could hold him in check.
Baldwin should have a solid week against his former teammate, Byron Maxwell.
29. Packers RB Eddie Lacy vs. Jaguars
Feast Mode will debut a slimmer frame against a Jacksonville defense that might be the fastest unit in the NFL.
30. Chiefs RB Spencer Ware vs. Chargers
With Jamaal Charles almost certainly on the shelf, Andy Reid's gameplan won't change; Ware should be in line for at least 20 touches.
Three high ranking guys who you should bench this week:
49ers RB Carlos Hyde vs. Rams
The Rams have a championship-caliber front seven, and Chip Kelly is going to want to throw the ball.
Titans RB Demarco Murray vs. Vikings
Vikings strong defense + Derrick Henry as the backup = Rough outing for Murray.
Carolina, not Denver, might have the best defense in the NFL.