Bell has been out since Aug. 19 with a foot injury. Initial reports indicated he may be out until after the Steelers' bye week (Week 5), but perhaps a lack of offensive spark and quick-healing capabilities made him listed as questionable this week.
Unable to play, the Steelers will continue with Isaac Redman, Felix Jones and Jonathan Dwyer.
Tight end Heath Miller will make a return of his own, getting back on the field for the first time since Week 16 of 2012. Miller tore his ACL and MCL, but has been practicing the last few weeks.
The Steelers (0-2) are one of the league's least productive offensive teams. Sorely lacking at the tight end position, and without consistent play from its offensive line, the team has managed just 75 yards rushing through its first two games.
The Steelers will also sit Derek Moye, who, with a touchdown catch against Cincinnati, is tied for team lead.
Here are the Steelers' inactives against Chicago:
QB Landry Jones, WR Derek Moye, RB Le'Veon Bell, Cortez Allen, CB Isaiah Green, OL Cody Wallace, NT Hebron Fangupo